M. tuberculosis: immunology and vaccination
نویسندگان
چکیده
منابع مشابه
M. tuberculosis: immunology and vaccination.
Tuberculosis is increasing. Current treatment regimens require at least 6 months, because latent or stationary phase organisms are difficult to kill. Such regimens do not achieve full compliance, and "directly observed therapy short course" (DOTS) is having less impact than expected. This worrying situation is aggravated by coinfection with human immunodeficiency virus (HIV), and by the increas...
متن کاملPediatric Immunology and Vaccination
While the majority of scientific evidence indicates that foals are immunocompetent at birth, vaccination is complicated by interference by passively transferred maternal antibody. In addition, there is considerable clinical evidence of poor resistance to disease or response to primary vaccinations in the first year of life. Against this background it is critical to identify and develop potent v...
متن کاملMucosal Immunology and Oral Vaccination
The mucosal surfaces of the gastrointestinal and respiratory tracts represent the principal portals of entry for most infectious agents. Hence, the development of vaccination strategies capable of inducing protective immune responses at the mucosal sites is a priority. Since the mucosal surfaces are exposed to a wide variety of antigens, the mucosal immune system has to discriminate between har...
متن کاملImmunology of tuberculosis.
Tuberculosis is a major health problem throughout the world causing large number of deaths, more than that from any other single infectious disease. The review attempts to summarize the information available on host immune response to Mycobacterium tuberculosis. Since the main route of entry of the causative agent is the respiratory route, alveolar macrophages are the important cell types, whic...
متن کاملImmunology of Tuberculosis
MTB ranks as the first worldwide pathogen latently infecting one third of the population and the second leading cause of death from a single infectious agent, after the human immunodeficiency virus (HIV). The development of vigorous and apparently appropriate immune response upon infection with M. tuberculosis in humans and experimental animals conflict with failure to eradicate the pathogen it...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2001
ISSN: 0000-0000,0903-1936
DOI: 10.1183/09031936.01.17305370